Author(s): J Bussel, J Mayer, L Cervinek, K Chojnowski, et. al. Abstract: S 435 Session topic: 32. Platelets disorders Background: ITP is characterized by autoantibody-directed platelet destruction mediated by activated monocyte Fc receptors which signal via spleen tyrosine kinase (syk). A Phase 2 trial of the oral syk inhibitor Fostamatinib (FOSTA) in...
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