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Lung Cancer News 1/2020 Slovak edition

Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

Tony S K Mok, Yi-Long Wu, Iveta Kudaba, et. al.

Lung Cancer News 1/2020 Slovak edition

Background First-line pembrolizumab monotherapy improves overall and progression-free survival in patients with untreated metastatic non-small-cell lung cancer with a programmed death ligand 1 (PD-L1) tumour proportion score (TPS) of 50% or greater. We investigated overall survival after treat­ment with pembrolizumab monotherapy in patients with a PD-L1 TPS of 1% or greater.   Methods This randomised, open-label, phase...

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