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Front-Line Pembrolizumab Is Promising Alternative to Chemotherapy for Advanced Gastroesophageal Junction and Gastric Cancers
18 septembra, 2020 8:01 pmJune 1, 2019 “Chemotherapy has been our only option for many years. These results introduce a potential alternative in pembrolizumab...
Najvýznamnejšie klinické správy z konferencie ASCO© 2019 v problematike nádorov gastrointestinálneho traktu
18 septembra, 2020 8:01 pmPočas prvého júnového týždňa tohto roku sa konal v Chicagu tradičný výročný kongres Americkej onkologickej spoločnosti (ASCO®). Ako obvykle v rámci prednášok...
Pembrolizumab (pembro) plus axitinib (axi) versus sunitinib as first-line therapy for metastatic renal cell carcinoma (mRCC): Outcomes in the combined IMDC intermediate/poor risk and sarcomatoid subgroups of the phase 3 KEYNOTE-426 study
18 septembra, 2020 8:01 pmAuthors: Brian I. Rini, Elizabeth R. Plimack, Viktor Stus, et. al. Abstract: 4500 Clinical Trial Registry Number: NCT02853331...
EV-201: Results of enfortumab vedotin monotherapy for locally advanced or metastatic urothelial cancer previously treated with platinum and immune checkpoint inhibitors
18 septembra, 2020 8:01 pmAuthors: Daniel Peter Petrylak, Arjun Vasant Balar, Peter H. O’Donnell, et. al. Abstract: LBA4505 Clinical Trial Registry Number:...
Interest of short hormonotherapy (HT) associated with radiotherapy (RT) as salvage treatment for metastatic free survival (MFS) after radical prostatectomy (RP): Update at 9 years of the GETUG-AFU 16 phase III
18 septembra, 2020 8:01 pmAuthors: Christian Carrie, Nicolas Magné, Patricia Burban-Provost, et. al. Abstract: 5001 Clinical Trial Registry Number: NCT00423475 Citation:...
Novel Targeted-Antibody Treatment Produced Responses in Nearly Half of Patients with Advanced Urothelial Cancer
18 septembra, 2020 8:01 pmJune 3, 2019 “If advanced urothelial cancer progresses following treatment with platinum-based chemotherapy and immunotherapy with checkpoint inhibitors there are...
SPRÁVA Z VÝROČNEJ KONFERENCIE AMERICKEJ ONKOLOGICKEJ SPOLOČNOSTI 2019 Genitourinárne malignity
18 septembra, 2020 8:01 pmV dňoch 1. – 5. júna 2019 sa v americkom Chicagu uskutočnila výročná konferencia Americkej onkologickej spoločnosti (ASCO®). Aj tento rok odzneli...
Baseline tumor-immune signatures associated with response to bempegaldesleukin (NKTR-214) and nivolumab
18 septembra, 2020 8:01 pmAuthors: Michael E. Hurwitz, Daniel C. Cho, Arjun Vasant Balar, et. al. Abstract: 2623 Clinical Trial Registry Number:...
Association between baseline disease characteristics and relapse-free survival (RFS) in patients (pts) with BRAF V600-mutant resected stage III melanoma treated with adjuvant dabrafenib (D) + trametinib (T) or placebo (PBO)
18 septembra, 2020 8:00 pmAuthors: Dirk Schadendorf, Reinhard Dummer, Axel Hauschild, et. al. Abstract: 9582 Citation: J Clin Oncol 37, 2019 (suppl;...
Five-year analysis on the long-term effects of dabrafenib plus trametinib (D + T) in patients with BRAF V600–mutant unresectable or metastatic melanoma
18 septembra, 2020 8:00 pmAuthors: Paul D. Nathan, Caroline Robert, Jean Jacques Grob, et. al. Abstract: 9507 Clinical Trial Registry Number: NCT01584648;...