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Association between baseline disease characteristics and relapse-free survival (RFS) in patients (pts) with BRAF V600-mutant resected stage III melanoma treated with adjuvant dabrafenib (D) + trametinib (T) or placebo (PBO)
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: Dirk Schadendorf, Reinhard Dummer, Axel Hauschild, et. al. Abstract: 9582 Citation: J Clin Oncol 37, 2019 (suppl;...
Five-year analysis on the long-term effects of dabrafenib plus trametinib (D + T) in patients with BRAF V600–mutant unresectable or metastatic melanoma
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: Paul D. Nathan, Caroline Robert, Jean Jacques Grob, et. al. Abstract: 9507 Clinical Trial Registry Number: NCT01584648;...
ASCO® 2019 – malígny melanóm Opäť krok dopredu
18 septembra, 2020 8:00 pm Leave your thoughtsMalígny melanóm bol roky v úzadí pri hodnotení príchodu nových metód terapie a inovatívnych preparátov. Len pred niekoľkými rokmi sa situácia obrátila...
Combination of niraparib and bevacizumab versus niraparib alone as treatment of recurrent platinum-sensitive ovarian cancer. A randomized controlled chemotherapy-free study—NSGO-AVANOVA2/ENGOT-OV24
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: Mansoor Raza Mirza, Elisabeth Avall-Lundqvist, Michael J. Birrer, et. al. Abstract: 5505 Clinical Trial Registry Number: NCT02354131...
Results from neoadjuvant chemotherapy followed by surgery compared to chemoradiation for stage Ib2-IIb cervical cancer, EORTC 55994
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: Gemma Kenter, Stefano Greggi, Ignace Vergote, et. al. Abstract: 5503 Clinical Trial Registry Number: NCT00039338 Citation:...
A randomized phase 3 trial of paclitaxel (P) plus carboplatin (C) versus paclitaxel plus ifosfamide (I) in chemotherapy-naive patients with stage I-IV, persistent or recurrent carcinosarcoma of the uterus or ovary: An NRG oncology trial
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: Matthew A. Powell, Virginia L. Filiaci, Martee Leigh Hensley, et. al. Abstract: 5500 Clinical Trial Registry Number:...
Správa z výročnej konferencie ASCO® 2019 – gynekologické malignity
18 septembra, 2020 8:00 pm Leave your thoughtsPočas prvého júnového týždňa tohto roku sa konal v Chicagu tradičný výročný kongres Americkej onkologickej spoločnosti (ASCO®). Tento rok bolo vybratých...
Neoadjuvant trastuzumab (H), pertuzumab (P), and chemotherapy versus trastuzumab emtansine (T-DM1) and P in human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC): Final outcome results from the phase III KRISTINE study
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: Sara A. Hurvitz, Miguel Martin, Kyung Hae Jung, et. al. Abstract: 500 Clinical Trial Registry Number: NCT02131064...
Trans-aTTom: Breast Cancer Index for prediction of endocrine benefit and late distant recurrence (DR) in patients with HR+ breast cancer treated in the adjuvant Tamoxifen – To offer more? (aTTom) trial
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: John Bartlett, Dennis Sgroi, Kai Treuner, et. al. Abstract: 505 Citation: J Clin Oncol 37, 2019 (suppl;...
Phase III MONALEESA-7 trial of premenopausal patients with HR+/HER2− advanced breast cancer (ABC) treated with endocrine therapy ± ribociclib: Overall survival (OS) results
18 septembra, 2020 8:00 pm Leave your thoughtsAuthors: Sara A. Hurvitz, Seock-Ah Im, Yen-Shen Lu, et. al. Abstract: LBA1008 Clinical Trial Registry Number: NCT02278120 ...